2021

主な論文・総説・著書

1. Ultrasound Image-guided Gene Delivery using Three-dimensional Diagnostic Ultrasound and Lipid-based Microbubbles  Daiki Omata, Lisa Munakata, Saori Kageyama, Yuno Suzuki, Tamotsu Maruyama, Tadamitsu Shima, Takumi Chikaarashi, Naoya Kajita, Kohji Masuda, Naoto Tsuchiya, Kazuo Maruyama, Ryo Suzuki.  Journal of Drug Targeting　30, 200-207, 2022．  DOI: 10.1080/1061186X.2021.1953510

2. Basic Research on Blood Coagulation Measurement of Extracorporeal Circulation Circuit Using Photoacoustic Imaging of LED Light Source.  Takahiro Wabe, Ryo Suzuki, Akimitsu Fujii, Yohsuke Uchida, Kazuo Maruyama, Yasutaka Uchida,  Sensors & Transducers, 253 (6), 1-8, 2021 http://www.sensorsportal.com
3. Ternary Complexes of pDNA, Neuron-Binding Peptide, and PEGylated Polyethyleneimine for Brain Delivery with Nano-Bubbles and Ultrasound  Yoko Endo-Takahashi, Ryo Kurokawa, Kanako Sato, Nao Takizawa, Fumihiko Katagiri, Nobuhito Hamano, Ryo Suzuki, Kazuo Maruyama, Motoyoshi Nomizu, Norio Takagi, Yoichi Negishi.  Pharmaceutics 13, 1003, 2021.   https://doi.org/10.3390/pharmaceutics13071003
4. Enhanced antitumor activity of combined lipid bubble ultrasound and anticancer drugs in gynecological cervical cancers.  Yamaguchi Kohei, Matsumoto Yoko, Suzuki Ryo, Nishida Haruka, Omata Daiki, Inaba Hirofumi, Kukita Asako, Tanikawa Michihiro, Sone Kenbun, Oda Katsutoshi, Osuga Yutaka, Maruyama Kazuo, Fujii Tomoyuki.  Cancer Science 112, 2493–2503, 2021  doi: 10.1111/cas.14907　
5. Lipid bubbles combined with low-intensity ultrasound enhance the intratumoral accumulation and antitumor effect of pegylated liposomal doxorubicin in vivo.  Inoru Yokoe, Daiki Omata, Johan Unga, Ryo Suzuki, Kazuo Maruyama, Yoshiharu Okamoto, Tomohiro Osaki.  Drug Delivery  28, 530-541, 2021　  doi: 10.1080/10717544.2021.1895907.
6. Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression.  Chisato Kinoshita, Kazue Kikuchi-Utsumi, Koji Aoyama, Ryo Suzuki, Yayoi Okamoto, Nobuko Matsumura, Kazuo Maruyama and Toshio Nakaki.   Communications Biology 4, 182-194, 2021  DOI:10.1038/s42003-021-01706-0
7. Enhanced Vascular Permeability by Microbubbles and Ultrasound in Drug Delivery.  Omata D, Munakata L, Maruyama K, Suzuki R. Biol Pharm Bull. 44(10):1391-1398, 2021  DOI: 10.1248/bpb.b21-00453
8. LED光音響イメージングによる血液体外循環回路内血液凝固予知保全のための輝度範囲選定　和部 崇洋，鈴木 亮，藤井 昭光，内田 庸助，丸山一雄，内田 恭敬　　材料技術　39，39-43, 2021
9. 腫瘍新生血管オープニングによるがん治療 大崎 智弘・横江 祈・鈴木 亮・小俣 大樹・丸山一雄 BIO Clinica 36(12), 53-55, 2021
10. 腫瘍新生血管オープニングによるがん治療 Cancer treatment by tumor neovascular opening  大崎 智弘・横江 祈・鈴木 亮・小俣 大樹・丸山一雄　　Medical Science Digest　47（10）,38−40，2021
11. 腫瘍新生血管オープニングによるがん治療  Cancer treatment by tumor neovascular opening  大崎 智弘・横江 祈・村端 悠介・鈴木 亮・小俣 大樹・丸山一雄　　細胞　53（2）, 107-109, 2021
12. 第10章　ファインバブルの医療への応用　鈴木亮、小俣大樹、宗像理紗、丸山一雄　　pp106-117　シーエムシー出版　6月18日　2021
13. OPINION 体外からDDSをコントロールする技術に期待　丸山一雄　Drug Delivery System, 36 (3), 160, 2021.